The review article titled as "Tumor suppressor genes and ROS: complex networks of interactions" by Vurusaner Beyza; Poli Giuseppe; Basaga Huveyda is published in Free Radical Biology and Medicine, 2012 Jan 1;52(1):7-18.
In a little while, the article ranked 6th in the list of the most downloaded Free Radical Biology and Medicine articles from ScienceDirect.
Beyza Vuruşaner talked about their studies:
I am PhD student working under the supervision of Hüveyda Başağa at Biology and Bioengineering Program, FENS. Başağa’s Lab focuses on signal transduction pathways regulating cellular functions such as senesence, proliferation or apoptosis at the molecular level. My project involves, studying the effects of reactive oxygen species, particularly cholesterol oxidation products and their signaling cascades, important in vascular remodeling.
Our review article which is titled as ''Tumor suppressor genes and ROS: Complex networks of interactions'' is a summary of the current state of understanding on interacting pathways between reactive oxygen species and major tumor suppressor genes which play critical role in cancer development. The review article is published in Free Radical Biology and Medicine (FRBM) which is an international, interdisciplinary journal that publishes original contributions and reviews on a broad range of topics relating to redox biology, signaling, biological chemistry and medical implications of free radicals, reactive oxygen species, oxidants and antioxidants. In 3 months, our review article ranked 6th in the list of most downloaded FRBM articles from Sciendirect.
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